NAD+ (Nicotinamide Adenine Dinucleotide) (Research Use Only)
Chemical Name: β-Nicotinamide adenine dinucleotide (oxidized form)
CAS Number:
53-84-9
Molecular Formula: C21H27N7O14P2
Molecular Weight: 663.43 g/mol
Appearance: White crystalline powder
Storage: Store at 2–8°C, protect from light and moisture
Form: Powder, soluble in water and aqueous buffers
Description
NAD+ is a pivotal coenzyme found in all living cells, playing an essential role in redox reactions, energy metabolism, and cellular signaling pathways. It serves as a substrate for enzymes involved in DNA repair, gene expression regulation, and longevity assurance mechanisms. Research into NAD+ supplementation examines its potential in combating age-related decline, metabolic diseases, and enhancing cellular health.
(Wikipedia)
(PubChem)
Research Applications
- Investigations into cellular metabolism and energy production
- Studies on DNA repair and genomic stability
- Examination of aging and longevity pathways
- Metabolic disease modeling including obesity and diabetes
- Mitochondrial function and oxidative stress research
Key References
Mechanism of Action
NAD+ functions as an electron carrier in metabolic redox reactions and as a substrate for sirtuins, PARPs, and other NAD+-dependent enzymes involved in DNA repair, gene expression, and aging. Its availability is crucial for maintaining cellular energy homeostasis and mitochondrial function.
Safety and Handling
Store NAD+ powder at 2–8°C, protected from moisture and light. Prepare solutions immediately before research use. NAD+ is generally well tolerated with no significant toxicity reported in scientific studies.
Disclaimer
For laboratory research use only. Not for human consumption, medical, veterinary, or diagnostic use. Provided for scientific research and educational applications only.
