TB500 (Research Use Only)
Chemical Name: TB500 (Synthetic Thymosin Beta-4 Region)
CAS Number:
885340-08-9
Molecular Formula:
C38H68N10O14
Molecular Weight: 889.02 g/mol
Sequence: N-Acetyl-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Appearance: White to off-white lyophilized powder
Storage: Store lyophilized powder at 2-8°C, protect from light
Form: Lyophilized powder, soluble in water or DMSO
Description
TB500 is a synthetic peptide representing an active region of thymosin beta-4. It is intensely studied for its wound healing, anti-inflammatory, and tissue repair properties. Research indicates TB500 promotes cellular migration, angiogenesis, collagen deposition, and reduces inflammation, making it a prominent candidate in regenerative medicine and repair therapies.
(Wikipedia)
(PubChem)
Research Applications
- Wound healing and tissue regeneration
- Anti-inflammatory mechanism studies
- Cell migration and angiogenesis research
- Collagen production and fibrosis modulation
- Potential use in orthopedic and cardiovascular research
Key References
Mechanism of Action
TB500 promotes tissue repair by modulating actin-cytoskeleton dynamics, enhancing cellular migration and angiogenesis. It also influences inflammatory mediators to reduce chronic inflammation and supports collagen synthesis aiding wound healing.
(PubMed)
Safety and Handling
Store TB500 lyophilized powder at 2-8°C. Reconstitute immediately before use with sterile water or DMSO. Minimal adverse effects are reported in research; proper aseptic handling is essential.
Disclaimer
For laboratory research use only. Not for human consumption, medical, veterinary, or diagnostic use. Information provided for scientific and educational purposes only.




