Semax (Research Use Only)
Chemical Name: Semax (ACTH 4-10 analog)
CAS Number:
80714-61-0
Molecular Formula: C37H51N9O10S
Molecular Weight: 813.92 g/mol
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Appearance: White to off-white powder
Storage: Store at 2–8°C, protect from light and moisture
Form: Lyophilized powder; soluble in water or DMSO
Description
Semax is a synthetic heptapeptide analogue of the ACTH (4-10) fragment with nootropic, neuroprotective, and anxiolytic properties. It modulates the expression of neurotrophins and supports neuronal survival under stress conditions such as hypoxia and glutamate toxicity. Semax is studied for its potential to improve cognitive functions, neuroplasticity, and brain circulation in various research models.
(Wikipedia)
(PubChem)
Research Applications
- Nootropic and cognitive enhancement studies
- Neuroprotection and stroke recovery research
- Investigation of neurotrophic factor modulation
- Anxiolytic and stress response modulation
- Brain circulation and plasticity improvement
Key References
Mechanism of Action
Semax modulates the expression of brain-derived neurotrophic factor (BDNF) and other growth factors that enhance neuronal survival, plasticity, and cognitive function. It also acts as an antioxidant and anti-inflammatory agent in neural tissues.
Safety and Handling
Store lyophilized Semax powder at 2–8°C. Prepare solutions immediately prior to research use under sterile conditions. Demonstrates a favorable safety profile with minimal adverse effects reported in animal and human research.
Disclaimer
For laboratory research use only. Not intended for human, veterinary, medical, or diagnostic applications. Provided for scientific and educational research purposes only.
