MT-2 (Melanotan 2 Acetate) (Research Use Only)

Name: MT-2
SKU: 513
Availability: InStock

Chemical Name: Melanotan II (MT-2) Acetate

CAS Number:
121062-08-6

Molecular Formula: C₅₀H₆₉N₁₅O₉

Molecular Weight: 1024.18 g/mol

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂

Appearance: White to off-white powder

Storage: Store at 2–8°C, protected from light

Form: Lyophilized powder; soluble in water or DMSO

Description

Melanotan 2 (MT-2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte stimulating hormone (α-MSH). It acts as a potent agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R) and induces pigmentation through melanogenesis, providing a tanning effect without sun exposure. Additionally, MT-2 is studied for its effects on sexual arousal, appetite suppression, and metabolic modulation in various research models.
(Wikipedia)
(PubChem)

Research Applications

Melanocortin receptor-mediated tanning and pigmentation studies
Investigation of sexual function and libido enhancement
Appetite regulation and weight management research
Neuroendocrine studies related to melanocortin pathways
Pharmacokinetic and pharmacodynamic profiling of cyclic peptides

Key References

Mechanism of Action

Melanotan 2 exerts its effects by activating melanocortin receptors, stimulating eumelanin production in melanocytes, and modulating central nervous system pathways involved in sexual behavior and appetite. Its cyclic structure enhances stability and bioavailability compared to endogenous α-MSH.

Safety and Handling

Store lyophilized Melanotan 2 acetate at 2–8°C. Prepare solutions immediately prior to use under sterile conditions. Preclinical data indicate a favorable safety profile; however, strict adherence to research use guidelines is critical.

Disclaimer

For laboratory research use only. Not for human, veterinary, medical, or diagnostic use. All information is intended for scientific research and educational purposes only.