GHK-Cu (Copper Peptide) (Research Use Only)
Chemical Name: Glycyl-L-Histidyl-L-Lysine Copper(II) Complex
CAS Number:
49557-75-7
Molecular Formula: C14H24CuN6O4
Molecular Weight: 403.9 g/mol
Sequence: Glycyl-L-Histidyl-L-Lysine complexed with Cu²⁺ (Copper(II) ion)
Appearance: Blue-colored solid, stable copper chelate complex
Storage: Store powder at 2–8°C, protect from moisture and light
Form: Lyophilized powder; soluble in water or DMSO
Description
GHK-Cu is a naturally occurring copper peptide complex found in human plasma, saliva, and urine. It exhibits potent regenerative and protective effects including stimulation of collagen and glycosaminoglycan synthesis, antioxidant, anti-inflammatory, and wound healing properties. GHK-Cu enhances skin remodeling and has shown promising potential in tissue repair, anti-aging, and modulation of gene expression involved in DNA repair and cancer suppression.
(Wikipedia)
(PubChem)
Research Applications
- Skin and tissue regeneration studies
- Wound healing and collagen synthesis research
- Anti-inflammatory and antioxidant mechanism studies
- Gene expression modulation and DNA repair pathways
- Potential anti-aging and cancer-related investigations
Key References
Mechanism of Action
GHK-Cu acts by delivering copper ions to tissues, facilitating cellular enzymatic activity crucial for collagen and elastin production. It modulates gene expression associated with tissue remodeling, antioxidant responses, and inflammatory pathways, contributing to enhanced wound healing and skin regeneration.
(PubMed)
Safety and Handling
Store GHK-Cu lyophilized powder at 2–8°C, protected from moisture. Reconstitute under sterile conditions for research use. It is well tolerated in preclinical studies with minimal adverse effects.
Disclaimer
For laboratory research use only. Not intended for human or veterinary use. All information is provided for scientific and educational applications only.




