AOD-9604 (Research Use Only)

Name: AOD-9604
SKU: 532
Availability: InStock

Chemical Name: AOD-9604 (Human Growth Hormone Fragment 176–191 Analog)

CAS Number:
221231-10-3

Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂

Molecular Weight: 1815.1 g/mol

Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (with disulfide bridge Cys7-Cys14)

Appearance: White to off-white lyophilized powder

Storage: Store at −20°C, protect from moisture and light

Form: Lyophilized peptide powder; soluble in DMSO and water

Description

AOD-9604 is a synthetic peptide analog of the C-terminal fragment of human growth hormone (hGH 176–191). It is researched for its selective lipolytic effects, stimulating fat metabolism without influencing blood glucose or growth hormone pathways. The peptide has been studied extensively for potential uses in obesity, metabolic syndrome, and cartilage repair, maintaining safety and minimal adverse effects in various preclinical and clinical evaluations.
(Wikipedia)
(PubChem)

Research Applications

Selective fat metabolism and lipolysis
Obesity and metabolic syndrome research
Cartilage repair and osteoarthritis studies
Insulin sensitivity and glucose homeostasis investigations
Safety and pharmacokinetics of peptide fragments

Key References

Mechanism of Action

AOD-9604 selectively stimulates lipolysis and inhibits lipogenesis by mimicking the C-terminal region of human growth hormone. It promotes fat breakdown without affecting insulin or growth hormone signaling pathways, making it a unique research peptide for studying metabolism and weight management.

Safety and Handling

Store lyophilized AOD-9604 at −20°C in airtight, light-protected packaging. Reconstitute immediately before use in sterile water or DMSO. Extensive research shows good safety and tolerability in animal and human studies.