5-amino-1mq
Price range: $20.00 through $50.00
5-Amino-1MQ (Research Use Only)
Chemical Name: 5-Amino-1-methylquinolinium iodide
CAS Number:
42464-96-0
Molecular Formula: C10H11N2+ I–
Molecular Weight: 286.11 g/mol
Appearance: Reddish-brown powder
Storage: Store at −20°C, protect from moisture
Form: Powder, soluble in DMSO and aqueous solutions
Description
5-Amino-1MQ (5-Amino-1-methylquinolinium iodide) is a synthetic small molecule studied for its inhibition of nicotinamide N-methyltransferase (NNMT), an enzyme involved in metabolic regulation and NAD+ biosynthesis. Research focuses on its potential to regulate cellular metabolism, promote enhanced muscle strength and endurance, and support fat metabolism pathways with minimal adverse effects in preclinical models.
(NNMT Overview)
(PubChem)
Research Applications
- Modulation of metabolism and NAD+ biosynthesis pathways
- Investigation of muscle stem cell proliferation and endurance improvement
- Studies on fat metabolism and obesity-related mechanisms
- Examination of epigenetic remodeling effects
- Potential exploration in anti-aging and chronic disease models
Key References
Mechanism of Action
5-Amino-1MQ acts as a potent inhibitor of NNMT, impacting methylation cycles and NAD+ metabolism. This modulation leads to enhanced cellular energy balance, improved mitochondrial function, and increased muscle stem cell activity demonstrated in preclinical models.
Safety and Handling
Store powder at −20°C, shielded from moisture and light. Dissolve in DMSO or aqueous buffer immediately before use. Exhibits a strong safety profile with no significant adverse effects
| Weight | N/A |
|---|---|
| Dimensions | N/A |
| 5amino1mqMG | 5mg, 50mg |
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